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Rank #7 · Score 6.5/10

Victoza

liraglutide · made by Novo Nordisk

Daily liraglutide for type 2 diabetes — the GLP-1 that started it all.

GLP-1 Injection (daily) Type 2 diabetes (adults and children 10+)

Quick verdict

Daily liraglutide for type 2 diabetes — the GLP-1 that started it all. Best for: Pediatric type 2 diabetes, or adults who do well on liraglutide.

Official site: Victoza.com · FDA prescribing label (PDF) · Savings program

Pros

  • Approved for pediatric T2D (10+)
  • CV benefit established
  • Generic liraglutide entering the market

Cons

  • Daily injection
  • Outclassed by weekly options for most adults

How Victoza works

Victoza contains liraglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist. It mimics gut hormones released after eating, producing three core effects (see our deeper explainer on how GLP-1s work):

Who Victoza is for

Pediatric type 2 diabetes, or adults who do well on liraglutide.

FDA-approved indications:

Who should avoid it

See our full safety guide for context on each contraindication.

How to take Victoza

Starting dose: 0.6 mg daily
Maximum dose: 1.8 mg daily

Side effects

Common (≥5% of users):

Serious warnings:

Most GI side effects appear during dose escalation and ease within 2–4 weeks. Eating smaller meals, avoiding greasy foods, and staying hydrated helps — our side-effect management guide covers practical tactics in detail. Persistent severe abdominal pain warrants immediate medical evaluation to rule out pancreatitis or gallbladder disease.

Where to get Victoza

Step-by-step pathways are covered in our guide to getting a GLP-1 prescription.

Cost

List price is approximately ~$815/mo. With commercial insurance and a savings card, many patients pay $0–$25/month. Without insurance, expect $500–$1,400/month depending on the program. Compare cash prices on GoodRx or Cost Plus Drugs.

Key evidence

The pivotal trial for Victoza is LEADER (NEJM, 2016): Liraglutide reduced major adverse cardiovascular events in adults with T2D at high CV risk.

Frequently asked questions

How quickly does Victoza work?

Most people notice reduced appetite within 1–2 weeks of starting Victoza. Meaningful weight or A1c changes typically appear after 8–12 weeks at a therapeutic dose, with maximum effects between 6 and 18 months.

Will I regain weight if I stop Victoza?

Clinical trials (STEP, SURMOUNT) show that most people regain a significant portion of lost weight within a year of stopping a GLP-1. These medications are generally considered long-term therapies, similar to blood pressure or cholesterol drugs.

Can I drink alcohol on Victoza?

There is no absolute contraindication, but alcohol can worsen nausea and increase the risk of pancreatitis and hypoglycemia (especially if combined with insulin or sulfonylureas). Many patients report decreased desire for alcohol on GLP-1s.

Is Victoza covered by insurance?

Coverage for type 2 diabetes is widespread under commercial plans and Medicare Part D. Prior authorization is common.

What happens if I miss a dose?

Take the missed dose the same day if you remember. If it is close to your next dose, skip it. Never double up.

Can I use Victoza during pregnancy?

No. GLP-1 medications should be stopped at least 2 months before a planned pregnancy. They are not recommended in pregnancy or breastfeeding due to limited safety data.

This review is informational only and does not constitute medical advice. Victoza is a prescription medication with a boxed warning. Discuss benefits and risks with a qualified healthcare provider before starting, stopping, or changing therapy.

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Further reading